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Association Agency out of Bodily Medication and you can Treatment, Taipei Tzu Chi Healthcare, Buddhist Tzu Chi Medical Basis, The brand new Taipei City, Taiwan

Affiliations Division from Rheumatology, Sensitivity, and you may Immunology, Service of Internal Drug, Kaohsiung Chang Gung Art gallery Healthcare, Kaohsiung, Taiwan, Chang Gung College College or university regarding Treatments, Kaohsiung, Taiwan

Affiliations Chang Gung University College regarding Medicine, Kaohsiung, Taiwan, Service out-of Obstetrics and Gynecology, Kaohsiung Chang Gung Art gallery Healthcare, Kaohsiung, Taiwan

Associations Office out-of Rheumatology, Allergy, and Immunology, Service away from Internal Drug, Kaohsiung Chang Gung Art gallery Hospital, Kaohsiung, Taiwan, Chang Gung University School of Drug, Kaohsiung, Taiwan

Fu-Mei Su,
Dung-Huan Liu,
Jia-Feng Chen,
Shan-Fu Yu,
Wen-Chan Chiu,
Chung-Yuan Hsu,

History

To grow an OSTAi equipment and you will compare that it into Federal Weakening of bones Base information into the 2013 (NOF 2013) getting limbs mineral occurrence (BMD) research one of Taiwan postmenopausal ladies.

Strategies

Taiwan Weakening of bones Association (TOA) presented a nationwide BMD questionnaire of the a coach strung having a great twin energy X-beam absorptiometry (DXA) anywhere between 2008 and you can 2011. All the people accomplished questionnaire, including demographics and you may chance things out-of osteoporotic fracture inside the FRAX device. We used the databases to research possible risk factors to have osteoporosis and you will followed the newest model by the Koh mais aussi al. to cultivate a danger directory through numerous changeable regression investigation and you will goods protection. We made use of the index opinions to prepare a straightforward formula (specifically OSTAi) to spot people that you prefer BMD aspect. Recipient doing work attribute (ROC) contour and also the city according to the bend (AUC) was used to compare the brand new sensitivity/specificity data regarding the model with that away from information from the NOF 2013.

Abilities

A total of twelve,175 Taiwan postmenopausal female enrolled in it questionnaire. The fresh list value are derived by the years and the entire body pounds away from the participants considering weighted odds of for every chance basis and you will the latest selected cutoff worthy of was lay on “-1”. You’ll find 6393 (52.5%) professionals whoever list worthy of is actually less than “-1” and you may whose danger of weakening of bones are 57.5% (). The fresh new AUC to have OSTAi and you may NOF 2013 had been 0.739 (95% count on interval (CI), 0.728–0.749, P 2 ), previous crack, high-risk therapy have fun with of this lowest bones mass or bone losings (elizabeth.g., glucocorticoid in an everyday dosage ? 5 mg prednisone otherwise equivalent getting ? 90 days), or condition otherwise condition of limbs loss (age.g., rheumatoid arthritis symptoms). The fresh diagnostic show off NOF 2013 to have anticipating weakening of bones within our analyzed population was then examined.

Statistical Data

I observed the mathematical research of the Koh et al. with modification. The potential risk products to own weakening of bones within the design invention procedure contained the danger issues regarding the FRAX device, where cultural grounds was not incorporated.

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